Primary stent implantation compared with primary balloon angioplasty for acute myocardial infarction: a meta-analysis of randomized clinical trials

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Acknowledgements

We would like to thank Jeremy Weedon, PhD, for helpful statistical advice, and David Antoniucci, MD, Cindy L. Grines, MD, Akiyoshi Kawashima, MD, Alfredo Rodriguez, MD, PhD, Shigeru Saito, MD, Bruno Scheller, MD, and Gregg W. Stone, MD, for contributing and/or verifying data.

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    For patients just outside of the 90-min time window, results of the PRAGUE-2 and DANAMI-2 trials suggest that transfer to a PCI-capable hospital is safe and decreases mortality compared with fibrinolysis,19–21 and is advised if it can be completed in 120 min or less (appendix p 3).4,15 Stent placement decreases target vessel revascularisation and subsequent myocardial infarction compared with balloon angioplasty alone.22,23 Several studies and meta-analyses show that drug-eluting stents (DES) reduce target vessel revascularisation compared with bare-metal stents (BMS),24–26 and some studies suggest that DES might also reduce major adverse cardiac events (MACE) in some patients.27–29

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