Comparison of atrial natriuretic peptide, B-type natriuretic peptide, and N-terminal proatrial natriuretic peptide as indicators of left ventricular systolic dysfunction
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A pilot study of <sup>13</sup>N-ammonia cardiac PET imaging to assess subacute cardiotoxicity following adjuvant intensity-modulated radiotherapy for locally advanced breast cancer
2020, Clinical ImagingCitation Excerpt :This can manifest in reduced epicardial coronary artery blood flow, or as an effect on the microvasculature with diffuse interstitial fibrosis, which can contribute primarily to diastolic dysfunction [28]. Left ventricular dysfunction is a common side effect of cancer treatment [29], and a decrease in its value in patients with left ventricular dysfunction or CAD has been reported [15,30–32]. In our study, and at a median follow-up time of 13 months (range 10–17 months), there was no change in LVEF.
Radiation-induced cardiac damage in early left breast cancer patients: Risk factors, biological mechanisms, radiobiology, and dosimetric constraints
2012, Radiotherapy and OncologyCitation Excerpt :It could be a useful tool in the evaluation of modern RT techniques, with respect to cardiac toxicity [37]. As LVEF values decreased in patients with left ventricular dysfunction or coronary artery disease [94,95], Perik et al., in the previously mentioned study, determined LVEF through radionuclide ventriculography and natriuretic peptide plasma concentrations in RT- and chemotherapy (CHT) – treated patients with left breast cancer. After a median of 2.7 years following chemotherapy and chest wall irradiation, subnormal LVEF values were observed in about 13% of the 54 patients examined [92].
Chronic Cardiac Failure
2010, Brocklehurst's Textbook of Geriatric Medicine and Gerontology
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Dr. Davidson was supported by a grant from the British Heart Foundation, London, United Kingdom.