MethodsMeasurements and day-to-day variabilities of left ventricular volumes and ejection fraction by three-dimensional echocardiography and comparison with magnetic resonance imaging
Section snippets
Subjects
Three-DE and magnetic resonance imaging were performed in 46 subjects including 36 men and 10 women (aged 51 ± 17 years, ranging 26 to 72). Group A included 15 healthy volunteers (aged 32 ± 7 years, men only). Group B included 31 patients (21 men and 10 women, aged 54 ± 18 years) with the diagnosis of ischemic heart disease demonstrating either regional (n = 19) or global (n = 12) wall motion abnormalities. All subjects studied were in sinus rhythm. The mean ± SD of their heart rate was 78 ± 10
Results
The mean ± SD of end-diastolic and end-systolic LV volumes and EF calculated by 3-DE and magnetic resonance imaging from all the subjects as well as from groups A and B are listed in Table I. Results from both techniques showed excellent correlation (r = 0.98, 0.98, and 0.98), with close limits of agreement (mean difference ± 2 SD)30 (−1.4 ± 27, −1.5 ± 21, and 0.2 ± 5.1) and nonsignificant differences (p = 0.6, 0.7, and 0.5) when calculating LV end-diastolic and end-systolic volume and EF,
Discussion
Accurate and reproducible assessment of LV volume and function has important clinical significance in most cardiac disorders. Three-DE has been shown to be accurate for evaluating LV volume and function comparison with many accepted techniques.20., 21., 22., 23., 24., 25., 26., 27. The results of this study demonstrate that 3-DE is a highly reproducible technique and is more favorable than magnetic resonance imaging in evaluating LV volume with low observer variability. This is consistent with
Acknowledgements
We would like to thank Rene Frowijn for his technical assistance throughout this work.
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