Coronary Artery DiseaseInfluence of lesion length on restenosis after coronary stent placement
Section snippets
Patients
This study includes a consecutive series of patients with symptomatic coronary artery disease who underwent coronary stent placement from January 1994 to October 1997. Exclusion criteria were only recent and chronic occlusions that precluded the assessment of lesion length.
Stent placement and poststenting treatment
The stent placement and poststenting therapy has been described previously.15, 16 Various stent types were implanted, including Palmaz-Schatz (Johnson & Johnson Interventional Systems Co., Warren, New Jersey), Inflow (Inflow
Clinical outcome
The study population comprised 2,736 patients. Using the cut-off value of 15 mm, 573 patients (21%) had long lesions and 2,163 patients had short lesions. The proportion of patients with long lesions remained relatively stable over the years of the study period: 17% in the first, 23% in the second, and 21% both in the third and fourth year (p = 0.20). Main baseline characteristics of the patients are listed in Table Iand compared between patients with long lesions and patients with short
Discussion
The main finding of this study is that long lesions are associated with a less favorable long-term clinical and angiographic outcome than shorter lesions, but without a significant influence on procedural success rate and incidence of subacute thrombosis. Greater lesion length exercises an independent negative effect that is further potentiated by placing multiple and overlapping stents.
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