Brief reportRelation of left ventricular chamber shape in patients with low (≤40%) ejection fraction to severity of functional mitral regurgitation
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Intraoperative transesophageal echocardiography for surgical repair of mitral regurgitation
2014, Journal of the American Society of EchocardiographyVentricular remodeling in children with left ventricular dysfunction secondary to various cardiomyopathies
2005, American Journal of CardiologyCitation Excerpt :We found a strong inverse relation between LV systolic function indexes (shortening fraction or the EF) and LV sphericity. In adults, ventricular remodeling is associated with a decrease in the LVEF, exercise tolerance, and survival and an increase in functional MR and the development of heart failure symptoms.8–14 However, there are limited data in children.
Rationale and design of the multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy of vasopressin antagonism in heart failure: Outcome study with Tolvaptan (EVEREST)
2005, Journal of Cardiac FailureCitation Excerpt :However, the study was underpowered with only 320 patients to detect significant differences in these end points. In a retrospective analysis, a trend toward lower total mortality was observed in the combined tolvaptan groups compared with placebo, particularly in patients with hyponatremia, renal dysfunction, or severe congestion at baseline.17 Tolvaptan has the potential to substantially advance the current management of congestion in heart failure.
Functional mitral regurgitation in chronic ischemic coronary artery disease: Analysis of geometric alterations of mitral apparatus with magnetic resonance imaging
2004, Journal of Thoracic and Cardiovascular SurgeryPharmacologic therapy for patients with chronic heart failure and reduced systolic function: Review of trials and practical considerations
2003, American Journal of CardiologyCitation Excerpt :The systemic vasoconstriction translates into increased afterload, which further reduces cardiac performance. In patients with HF, a marked increase in the LV diastolic pressure may be responsible for changes in the shape of the left ventricle from an ellipsoid to a more spherical configuration.46,47 This change in ventricular geometry may result in papillary muscle rearrangement and secondary mitral insufficiency.48,49
Prevalence and severity of mitral regurgitation in chronic systolic heart failure
2003, American Journal of Cardiology