The Effects of Nonpulsatile Blood Flow on Canine Lungs

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Cited by (43)

  • Pulmonary Bleeding during Right Ventricular Support after Left Ventricular Assist Device Implantation

    2016, Journal of Cardiothoracic and Vascular Anesthesia
    Citation Excerpt :

    Under continuous-flow perfusion of the lungs, a significant increase in pulmonary artery pressure and an increase of pulmonary vascular resistance are observed. These effects seem to occur in a time-dependent manner and are not necessarily reversible when pulsatile perfusion is restored.10,12 As an explanation, a time-dependent change in pulmonary vascular resistance under non-pulsatile perfusion, especially with high flow rates, is favored.12

  • Anatomic biventricular correction by taking down bicaval Glenn shunt

    2000, Annals of Thoracic Surgery
    Citation Excerpt :

    In this case, we initially performed bicaval Glenn shunt with retained pulsatile flow from both the SVC and IVC to the right PA, without shutting down the communication between the SVC and RA. Some articles have reported the effectiveness of pulsatile flow for suppressing the increase of pulmonary vascular resistance [7–9]. Samanek and associates [9] showed that a pulsatile flow distributes more pulmonary blood flow than a nonpulsatile flow does.

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Supported by grants from the National Institutes of Health (HE-09385-03) and the Michigan Heart Association.

*

Evarts A. Graham Travelling Fellow for 1966–67 (supported by the American Association for Thoracic Surgery) and holder of a travelling grant from the National Heart Foundation of Australia. Present address: Green Lane Hospital, Auckland SE3, New Zealand.

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