ArticlesInhibition of platelet activity by S-nitrosoglutathione during coronary angioplasty
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Cited by (199)
Photoactivation of tDodSNO induces localized vasodilation in rats: Metabolically stable S-nitrosothiols can act as targeted nitric oxide donors in vivo
2022, Nitric Oxide - Biology and ChemistryEffects of nitrite and far-red light on coagulation
2021, Nitric Oxide - Biology and ChemistryModulating the Bioactivity of Nitric Oxide as a Therapeutic Strategy in Cardiac Surgery
2021, Journal of Surgical ResearchInvestigation of S-Nitrosoglutathione in stroke: A systematic review and meta-analysis of literature in pre-clinical and clinical research
2020, Experimental NeurologyCitation Excerpt :With the potential of regulating platelet functions and hemodynamics, the effects of GSNO were also investigated in other vascular disease studies besides ischemic stroke (Supplemental Table). Early-phase clinical studies found GSNO increased left ventricular function by tonic releasing of NO (Rassaf et al., 2006), improved systemic vasodilation and hemodynamics (Rassaf et al., 2002), reduced maternal mean arterial pressure, platelet activation, and uterine artery resistance for preeclampsia (Everett et al., 2014; Lees et al., 1996), increased the clitoral blood flow in healthy subjects (Souto et al., 2011), and prevented platelet activity after percutaneous transluminal coronary angioplasty (Langford et al., 1994). We found it is hard to do meta-analysis of the infarct size with the preclinical studies, due the heterogeneity of results expression: 2/6 studies only provided qualitative results (Khan et al., 2015b; Khan et al., 2015c), 2/6 studies used infarct volume (Khan et al., 2006; Khan et al., 2005), 2/6 study expressed corrected percentage of infarct (Sakakima et al., 2012; Parent et al., 2015).
Flow cytometry
2019, PlateletsElectrochemical detection of nitric oxide and S-nitrosothiols in biological systems: Past, present & future
2018, Current Opinion in ElectrochemistryCitation Excerpt :In all cases the performances of the prepared sensors depend on several parameters such as (i) the electrode material and the conditions of polymerization that affect the properties of an electrochemically prepared polymer modified electrode [18•], (ii) the potential necessary for NO detection that depends on the nature of the substrate, the electrocatalytic properties of the membrane and on the surface roughness [31] and (iii) the electrochemical techniques that are usually simple amperometry, pulsed chronamperometry, differential normal pulse amperometry and differential normal pulse voltamperometry [17•]. In order to be transported and stored in biological fluids, NO binds to the sulfhydryl groups of peptides and proteins forming S-nitrosothiols that play important roles in several physiological functions [54–63] and physiopathological events [64–73]. They exist in biological media at concentrations that vary between tenth of nanomolar to less than ten micromolar [74••,75•,76••] and there is no gold standard method to determine their biological concentrations.