Randomised trial of excimer laser angioplasty versus balloon angioplasty for treatment of obstructive coronary artery disease
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The Ongoing Saga of the Evolution of Percutaneous Coronary Intervention: From Balloon Angioplasty to Recent Innovations to Future Prospects
2022, Canadian Journal of CardiologyCitation Excerpt :It was therefore perceived as a useful tool to reduce restenosis rates. However, the initial enthusiasm for this technique was blunted by observational studies that showed high rates of restenosis and complications, mostly due to the premature use of a young technology, because the first-generation coronary laser was associated with unacceptable heat production, leading to the risk of dissection and sometimes perforation.48,49 In the 1990s, technological improvements led to the introduction of excimer laser coronary angioplasty (ELCA; Philips, Amsterdam, The Netherlands), using different beams leading to less heat production and continuous saline flushing, therefore increasing safety.
Abrasion, grinding, pulverization, vaporization, and extraction: Debulking options for percutaneous coronary interventions of calcified coronary lesions
2022, Debulking in Cardiovascular Interventions and Revascularization Strategies: Between a Rock and the HeartContemporary technologies to modify calcified plaque in coronary artery disease
2021, Progress in Cardiovascular DiseasesCitation Excerpt :Fourth, ELCA can vaporize thrombi,46 expanding its use in acute coronary syndromes.47 Early studies reported procedural success rates of 77–90% with ELCA,48–51 complication rates of 4–7%,51,52 restenosis rates in 46%,52 perforations in 1–2%,48,49 and in-hospital mortality of 0.5–1.5%,48,49 with no clear benefit over conventional angioplasty.50 Nevertheless, ELCA may be particularly useful compared to other forms of atherectomy in cases of venous grafts, in-stent restenosis, and treating thrombi.
Simple percutaneous coronary interventions using the modification of complex coronary lesion with excimer laser
2019, Cardiovascular Revascularization MedicineCitation Excerpt :A bubble in the liquid environment results in the free ejection of debris, which is believed to be the dominant mechanism for tissue removal for ELCA (photomechanical effect) [3]. Despite these favorable effects, ELCA at the beginning showed no benefit aside from balloon angioplasty alone with respect to the initial and long-term clinical and angiographic outcomes in PCI [4]. However, several important factors that govern successful laser application have been developed to improve the efficacy and safety of ELCA.
Challenges With Severe Coronary Artery Calcification in Percutaneous Coronary Intervention: A Narrative Review of Therapeutic Options
2018, Canadian Journal of CardiologyEarly outcome of high energy Laser (Excimer) facilitated coronary angioplasty ON hARD and complex calcified and balloOn-resistant coronary lesions: LEONARDO Study
2015, Cardiovascular Revascularization Medicine