Research PaperA controlled trial of colchicine in primary biliary cirrhosis: Trial design and preliminary report
References (31)
- et al.
A prospective controlled trial of azathioprine in primary biliary cirrhosis
Gastroenterology
(1976) - et al.
Azathioprine in primary biliary cirrhosis: A preliminary report of an international trial
Gastroenterology
(1980) - et al.
Beneficial effect of azathioprine and prediction of prognosis in primary biliary cirrhosis
Gastroenterology
(1985) - et al.
Randomised trial of chlorambucil for primary biliary cirrhosis
Gastroenterology
(1986) - et al.
Treatment of cirrhosis with colchicine. A double-blind randomised trial
Gastroenterology
(1979) - et al.
Clinical pattern and course of disease in primary biliary cirrhosis based on an analysis of 236 patients
Gastroenterology
(1980) - et al.
Granulomas in primary biliary cirrhosis: A prognostic feature
Gastroenterology
(1981) - et al.
d-Penicillamine treatment improves survival in primary biliary cirrhosis
Lancet
(1981) - et al.
A controlled trial of d-penicillamine therapy in primary biliary cirrhosis
Lancet
(1977) - et al.
Is P.B.C. an immune complex disease
Lancet
(1977)
The effects of cyclosporin A on suppressor and inducer T-lymphocytes in primary biliary cirrhosis
Lancet
(1980)
Potential pathogenic mechanisms in primary biliary cirrhosis
Semin Liver Dis
(1981)
In vitro effect of Cyclosporin A on immunoglobulin production and concanavalin A induced suppression in primary biliary cirrhosis
Gut
(1986)
Primary biliary cirrhosis
A prospective trial of d-penicillamine in primary biliary cirrhosis
N Engl J Med
(1982)
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Management of Autoimmune and Cholestatic Liver Disorders
2009, Clinics in Liver DiseaseCitation Excerpt :Colchicine inhibits microtubule polymerization by binding to tubulin, ultimately preventing mitosis. Its mechanism of action in the treatment of PBC remains unknown, but it has been studied in several small studies with varying degrees of success.55–58 Although there was improvement in serum biochemical parameters, there was no histologic improvement or survival benefit seen except in the trial by Kaplan and colleagues.
Portal pressure is of significant prognostic value in primary biliary cholangitis
2023, Liver InternationalPortal hypertension in primary biliary cholangitis: prevalence, natural history and histological correlates
2021, European Journal of Gastroenterology and Hepatology
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Present address: Liver Unit, King's College Hospital, London, U.K.
Copyright © 1987 Published by Elsevier Ireland Ltd.