Clinical Studies
Double-oblique free-breathing high resolution three-dimensional coronary magnetic resonance angiography

https://doi.org/10.1016/S0735-1097(99)00223-5Get rights and content
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Abstract

OBJECTIVES

The goal of the present study was to develop a strategy for three-dimensional (3D) volume acquisition along the major axes of the coronary arteries.

BACKGROUND

For high-resolution 3D free-breathing coronary magnetic resonance angiography (MRA), coverage of the coronary artery tree may be limited due to excessive measurement times associated with large volume acquisitions. Planning the 3D volume along the major axis of the coronary vessels may help to overcome such limitations.

METHODS

Fifteen healthy adult volunteers and seven patients with X-ray angiographically confirmed coronary artery disease underwent free-breathing navigator-gated and corrected 3D coronary MRA. For an accurate volume targeting of the high resolution scans, a three-point planscan software tool was applied.

RESULTS

The average length of contiguously visualized left main and left anterior descending coronary artery was 81.8 ± 13.9 mm in the healthy volunteers and 76.2 ± 16.5 mm in the patients (p = NS). For the right coronary artery, a total length of 111.7 ± 27.7 mm was found in the healthy volunteers and 79.3 ± 4.6 mm in the patients (p = NS). Comparing coronary MRA and X-ray angiography, a good agreement of anatomy and pathology was found in the patients.

CONCLUSIONS

Double-oblique submillimeter free-breathing coronary MRA allows depiction of extensive parts of the native coronary arteries. The results obtained in patients suggest that the method has the potential to be applied in broader prospective multicenter studies where coronary MRA is compared with X-ray angiography.

Abbreviations

CNR
contrast-to-noise ratio
ECG
electrocardiogram/electrocardiographic
LAD
left anterior descending coronary artery
LCX
left circumflex coronary artery
LM
left main coronary artery
MR
magnetic resonance
MRA
magnetic resonance angiography
RCA
right coronary artery
RHD
right hemidiaphragm
ROI
region of interest
SNR
signal-to-noise ratio
TE
echo time
TFE-EPI
turbo field echo-echo planar imaging
TR
repetition time
2D
two-dimensional
3D
three-dimensional

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