Journal of the American Society of Echocardiography
Original articleLongitudinal ventricular function: normal values of atrioventricular annular and myocardial velocities measured with quantitative two-dimensional color doppler tissue imagingā
Section snippets
Study patients
The study population initially comprised 143 individuals (age 59 Ā± 18 years; range: 22 to 89 years). We wished to avoid the potential bias of studying volunteer patients. All individuals were identified from the patient lists of local primary care physicians. Patients with no known cardiovascular disease or other chronic illnesses and no recent (<1 year) visit to their family physician were selected and received a written invitation to visit the department for echocardiography. None were taking
General echocardiographic and doppler characteristics
The study patients were classified into 4 groups aged 20 to 39 (group 1, n = 29), 40 to 59 (group 2, n = 30), 60 to 79 (group 3, n = 47), and ā„80 (group 4, n = 17) years. Table 1 shows general echocardiographic characteristics for different age groups.
There was a statistically significant lower body surface area with age principally because younger volunteers were taller than their older counterparts. However, despite these demographic distinctions, there were no statistically significant
Discussion
The LV wall is composed of both circular and longitudinal myocardial fibers. The later fibers dominate in subepicardial and subendocardial layers and in the papillary muscles. Apart from anatomic, there are important functional distinctions with the longitudinal fibers contracting earlier than the circular fibers.25, 26
Cardiac disorders can impair both longitudinal and radial contractile function. However, it has been suggested that in pathologic conditions (eg, myocardial ischemia or
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Dr Nikitin was supported by an international traveling research fellowship grant from the Wellcome Trust.