Original articlePrevalence of risk factors, and not gender per se, determines short- and long-term survival after coronary artery bypass surgery☆
Section snippets
Methods
The authors used a prospective multicenter observational database of patients undergoing CABG surgery. All patients enrolled in the study were undergoing elective CABG surgery and not enrolled in another research study. A total of 100 randomly selected patients were required from each of the 24 medical centers.
Two thousand four hundred seventeen patients who underwent CABG surgery at the 24 United States centers were enrolled into the study between September 1991 and September 1993 and followed
Results
Of the 2,048 patients, 460 (22%) were females and 1,588 (78%) were males. The preoperative variables listed in Table 1 were compared between male and female patients and are presented in Table 2. At the time of surgery, women were older and had more comorbid conditions, including congestive heart failure, higher Canadian classification for angina and New York Heart Association classification for congestive heart failure, diabetes mellitus, anemia, hypertension, vascular disease, and/or prior
Discussion
The authors found that gender per se did not confer risk for adverse outcome after CABG surgery, but the prevalence of risk factors such as advanced age, vascular disease, anemia, prior myocardial infarction, congestive heart failure, and diabetes did equally for both women and men. The implications of the present study suggest that surgical outcome is not determined by gender and therefore irreversible but that there exist potentially modifiable risk factors for women (as there are for men),
Acknowledgements
The authors wish to thank Diane Beatty and Brenda Xavier for their technical assistance. Participating Multicenter Study of Perioperative Ischemia (McSPI) Research Group Institutions and Investigators: Baylor College of Medicine, Houston, TX, Randall Clark, MD, Patrick E. Curling, MD, Salwa Shenaq, MD; Beth Israel Hospital, Boston, MA, Mark E. Communale, MD; Brigham and Women’s Hospital, Boston, MA, Simon Body, MD, Rosemarie Maddi, MD; Cedars-Sinai Medical Center, Los Angeles, CA, Arnold S.
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Supported by a grant from the Ischemia Research and Education Foundation, San Francisco, CA.