Clinical InvestigationImaging and Diagnostic TestingThe prevalence of bicuspid aortic valve in newborns by echocardiographic screening
Section snippets
Methods
All live born consecutive neonates delivered at Obstetrics and Gynecology Department of a university hospital in a period from May 2002 to May 2003 were included in the study group. Parental consents were obtained for each neonate. The ethics committee of our institution approved the study (approval no: 22-2002/402). All neonates were screened by 1 of the authors within the first 72 hours at the Department of Pediatric Cardiology of the same university hospital.
One thousand seventy five
Results
BAV was identified in 5 neonates without any other congenital cardiac or extracardiac malformations, with a prevalence of 4.6 in 1000 live births. Gestational ages and birth weights of 5 newborns (4 boys, 1 girl) with BAV ranging from 39 to 40 (mean ± SD = 39.4 ± 0.5) weeks and 3050 to 4500 (mean ± SD = 3459 ± 609) g, respectively. The prevalence of BAV by sex was 7.1 of 1000 in male neonates and 1.9 of 1000 in female neonates. All newborns with BAV were asymptomatic. None had an ejection click
Discussion
BAV is generally accepted as the most common congenital cardiac malformation, occurring in approximately 1% to 2% of the general population.1, 2 In previous studies, the prevalence of BAV was reported with a range of 0.59% to 1.37%, largely from autopsy series.2, 3, 4, 5
In the largest autopsy series, Larson and Edwards3 found 293 (1.37%) BAVs in 21 417 consecutive autopsies. However, they did not mention the sex distribution of cases. Pauperio et al4 evaluated 2000 aortic valves obtained from
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