CardiomyopathyNew Classification Scheme of Left Ventricular Noncompaction and Correlation With Ventricular Performance
Section snippets
Methods
All patients undergoing transthoracic echocardiography at Mount Sinai Medical Center from September 10, 2005 to January 5, 2006 were eligible for inclusion. Of the >4,000 echocardiograms performed during the study period, we randomly selected 500 from daily digitally stored studies. Reviewers selecting patients for study inclusion were blinded to patient demographic and echocardiographic characteristics. After being selected for inclusion, each echocardiogram was reviewed before obtaining
Results
Of the 500 patients originally selected for inclusion in the study, 74 patients (14.8%) were excluded because they had evidence of congenital heart disease, hypertrophic or infiltrative cardiomyopathy, or documented coronary artery disease. An additional 46 patients (9.2%) were excluded because the apex was not adequately visualized for full analysis. Of the remaining 380 patients, 60 (15.8%) had evidence of some degree of noncompaction. There were no significant differences between controls
Discussion
Isolated noncompaction of the left ventricle is a recently described cardiomyopathy, often detected incidentally. We sought to assess the prevalence and spectrum of the disease, correlate the severity of noncompaction with characteristics of left ventricular performance, and evaluate 2 novel classification schemes. LVNC was originally believed to be an extremely rare disorder, with early estimates of prevalence ranging 0.014% to 0.045%,5, 6 although more recent work has estimated the prevalence
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Cited by (0)
Adam Belanger was supported by a grant from the Doris Duke Clinical Research Foundation, New York, New York.