Journal of the American Society of Echocardiography
Original articleTwo-dimensional strain–a novel software for real-time quantitative echocardiographic assessment of myocardial function
Section snippets
Methods
A total of 20 patients with acute MI, admitted to the intensive coronary care department, underwent conventional transthoracic echocardiography. The control group included 10 healthy individuals with normal echocardiography. Standard 4-chamber, 3-chamber (apical long axis), and 2-chamber views of the left ventricle (LV) (Vivid 7, General Electric, Horten, Norway) (2.5-MHz transducer) were obtained from the apex at end-expiratory apnea and were stored in cineloop format for subsequent offline
Comparison between myocardial velocities, strain, and strain rate by 2D strain and wall-motion analysis
Mean age was 58 years (43-74 years). Mean ejection fraction by conventional echocardiography was 35% (25%-45%). In all, 9 patients had inferoposterior MI, 1 had posterolateral MI, and 10 had anterior MI. Single-vessel coronary artery disease was detected in 8 patients, 2-vessel coronary artery disease in 7, and 3-vessel coronary artery disease in 5.
Wall-motion analysis
As shown in Table 1, on the basis of conventional imaging, 539 cardiac segments were suitable for analysis of wall motion. Among 172 infarct
Discussion
The quantification of segmental LV function has a central role in echocardiography. Quantitative ultrasonic tissue characterization with integrated backscatter had been proposed for differentiation of infarct tissue from normal myocardium. This technique is useful, however, it is limited to the parasternal views.7 Time to onset of regional relaxation has been proposed as a parameter of regional myocardial function and was defined as the time from the R wave of the electrocardiographic trace to
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