Viewpoint
From knowledge to practice in chronic cardiovascular disease: a long and winding road

https://doi.org/10.1016/j.jacc.2003.12.043Get rights and content
Under an Elsevier user license
open archive

Abstract

Although clinical practices evolve over time, the translation of specific research evidence into clinical practice is unpredictable, inconsistent, and complex. In this paper, we use examples from chronic cardiovascular conditions to: 1) highlight two types of care gaps; 2) describe the most common potential barriers to the application of evidence into clinical care; and 3) outline which of the strategies for translating evidence into clinical care have been shown to be ineffective, which strategies have been shown to be effective and to describe some untested approaches that hold promise.

Abbreviations

ACE
angiotensin-converting enzyme
HF
heart failure
HOPE
Heart Outcomes Prevention and Evaluation study
MI
myocardial infarction
RCT
randomized clinical trial

Cited by (0)

Drs. Majumdar and McAlister are Population Health Investigators, supported by the Alberta Heritage Foundation for Medical Research, and New Investigators, supported by the Canadian Institutes of Health Research.