Cardiac rehabilitation after myocardial infarction in the community

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Objectives

The aim of this study was to examine participation in cardiac rehabilitation after myocardial infarction (MI) by age and gender and the association of participation with survival.

Background

Lesser participation in cardiac rehabilitation has been reported for women and the elderly.

Methods

All incident MIs in Olmsted County were validated. Baseline characteristics and outcomes were ascertained from the medical record. Logistic regression examined the association between participation, age, and gender. Propensity scores were used to examine the association between participation and outcome.

Results

Among 1,821 persons with incident MI (58% men, 46% age >70 years), 55% participated in cardiac rehabilitation. Participants were more likely to be men, younger, and have fewer comorbidities (p < 0.01 for all comparisons). After adjustment, women were 55% less likely to participate than men (odds ratio [OR] 0.45, 95% confidence interval [CI] 0.34 to 0.60), and persons 70 years or older were 77% less likely to participate than persons younger than 60 (OR 0.23, 95% CI 0.16 to 0.33). Participants had a lower risk of death and recurrent MI at three years (p < 0.001 and p = 0.049, respectively). The survival benefit associated with participation was stronger in more recent years (relative risk [RR] for 1998 vs. 1982 0.28, 95% CI 0.18 to 0.43; RR for 1990 vs. 1982 0.41, 95% CI 0.33 to 0.52).

Conclusions

Approximately half of the patients participated in cardiac rehabilitation after MI. Participation did not increase over time. Women and elderly persons were less likely to participate, independently of other characteristics. Participation in rehabilitation was independently associated with decreased mortality and recurrent MI, and its protective effect was stronger in more recent years.

Abbreviations and acronyms

AMI
acute myocardial infarction
CHD
coronary heart disease
CI
confidence interval
CK
creatine phosphokinase
ECG
electrocardiogram/electrocardiographic
LVEF
left ventricular ejection fraction
MI
myocardial infarction
OR
odds ratio
RR
relative risk

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Supported in part by grants from the Public Health Service, National Institutes of Health (AR30582 and HL59205) and the Fanny E. Rippel Foundation. Dr. Roger is an Established Investigator of the American Heart Association.