State-of-the-Art Paper
Clinical Characteristics of Peripartum Cardiomyopathy in the United States: Diagnosis, Prognosis, and Management

https://doi.org/10.1016/j.jacc.2011.03.047Get rights and content
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Peripartum cardiomyopathy is a pregnancy-associated myocardial disease characterized by the development of heart failure due to marked left ventricular systolic dysfunction. Although the disease is relatively uncommon, its incidence is increasing, and it can be associated with important and lasting morbidity and with mortality. Peripartum cardiomyopathy seems to affect women in different parts of the world but with considerable differences in clinical presentation. The purposes of this review are to describe the clinical profile of peripartum cardiomyopathy in the United States and to provide recommendations for the diagnosis and the management of this disease.

Key Words

cardiomyopathy
heart failure
pregnancy

Abbreviations and Acronyms

ACE
angiotensin-converting enzyme
ARB
angiotensin receptor blocker
BNP
brain natriuretic peptide
DCM
dilated cardiomyopathy
HF
heart failure
ICD
implantable cardioverter-defibrillator
LV
left ventricular
LVEF
left ventricular ejection fraction
MRI
magnetic resonance imaging
PPCM
peripartum cardiomyopathy

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Dr. Elkayam has reported that he has no relationships to disclose.