Original ResearchMolecular Imaging for Efficacy of Pharmacologic Intervention in Myocardial Remodeling
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Key Words
collagen
remodeling
radionuclide imaging
angiotensin receptors
angiotensin-converting enzyme
mineralocorticoids
heart failure
Abbreviations and Acronyms
ACE-I
angiotensin-converting enzyme inhibitor
ARB
angiotensin receptor blocker
ASMA
alpha smooth muscle actin
C
captopril
CRIP
Cy5.5-RGD imaging peptide
L
losartan
LV
left ventricular
MI
myocardial infarction
RGD
Arg-Gly-Asp.
S
spironolactone
SARA
selective aldosterone receptor antagonist
sCRIP
scrambled Cy5.5-RGD imaging peptide
99mTc
technetium-99m
Cited by (0)
Dr. van den Borne was partially supported by a grant from the Netherlands Heart Foundation (2006R013). Dr. Lovhaug is an employee of GE Healthcare, involved in tracer preparation for the imaging studies. Dr. Pitt is a consultant to Pfizer, Merck, Takeda, Astra Zeneca, Synvista, Novartis, and Nile therapeutics but has no conflicts directly with the project. H. William Strauss, MD, acted as Guest Editor for this paper.
Copyright © 2009 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.