Epidemiology of Syncope/Collapse in Younger and Older Western Patient Populations
Section snippets
Syncope and the Framingham studies
The Framingham series illustrates this difficulty of comparisons for the epidemiology of syncope vis-à-vis variations in definitions and methodologies. For example, in the first Framingham cohort of 1985 the authors reported a first syncope episode in 3% of men and 3.5% of women over a 26-year follow up period (mean age of cohort was 46 ranging from 30 to 62 years). Of these, the majority had experienced an isolated syncope.5
The cumulative incidence of syncope during a 4-year follow-up in the
Conclusion
In conclusion, syncope is a common problem in the general population. Its age distribution is bi-modal or tri-modal according to recent studies, peaking in teenagers and the elderly. Although several studies have been performed with young subjects, the incidence of syncope in the elderly in the general population is less well studied, with the exception of the recent TILDA dataset.
The lifetime cumulative incidence of syncope is much higher in women than in men. Reflex syncope remains more
Statement of Conflict of Interest
The authors of this article have no pertinent conflicts of interest to report.
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2022, European Journal of Internal MedicineCitation Excerpt :The lifetime cumulative incidence of syncope can reach ∼35%, is more common in women, and its age distribution is bi-modal, peaking in teenagers and the elderly [3–7]. In the younger age group, VVS is almost the exclusive cause, compared to the older population in which the causes are more varied [3–5]. Different studies report a constant frequency of syncope in ED, with an incidence of approximately 1% of all attendances [8–11], and a proportional in-hospital admission rate that ranges from 12–83% (∼ 50%) [3,7,10,12–15].
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2021, Brain, Behavior, and ImmunityCitation Excerpt :Concerning VVS, the median age of peak occurrence is 15 years and a second peak occurs in older adults ≥ 70 years (Kenny et al., 2013); moreover, females experience almost twice the rate of VVS as males (Kenny et al., 2013). VVS can generate significant interruptions in activities of daily living and reduced quality of life (Kenny et al., 2013) and the most common situations which trigger VVS are acute heat stress, prolonged standing, pain, and emotional stress (Kenny et al., 2013; Ganzeboom et al., 2003; O'Dwyer et al., 2011). VVS can be assessed by exposing individuals to orthostatic stress in controlled settings (Baker et al., 2019; Freeman and Chapleau, 2013).
One-year outcomes in patients with high-risk and low-risk syncope
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Statement of Conflict of Interest: see page 362.