Clinical trial data, including those from MADIT-CRT, support the use of cardiac resynchronization therapy in patients with asymptomatic and mildly symptomatic heart failure and ventricular dyssynchrony. However, important questions remain about which of these patients benefit most from this therapy.
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W. T. Abraham has acted as a consultant for and received research support from Biotronik, Medtronic and St. Jude Medical. J. Holzmeister has received consultancy fees from Biotronik and St Jude Medical and research support from Biotronik, Boston Scientific, and St Jude Medical.
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Holzmeister, J., Abraham, W. Indications for ICD–CRT in mildly symptomatic heart failure. Nat Rev Cardiol 7, 7–8 (2010). https://doi.org/10.1038/nrcardio.2009.196
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DOI: https://doi.org/10.1038/nrcardio.2009.196
