Role of altered beta-adrenoceptor signal transduction in the pathogenesis of cirrhotic cardiomyopathy in rats
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Perioperative Cardiovascular Risk Assessment and Management in Liver Transplant Recipients: A Review of the Literature Merging Guidelines and Interventions
2024, Journal of Cardiothoracic and Vascular AnesthesiaPotential cardioprotective influence of bupropion against CCl4-triggered cirrhotic cardiomyopathy
2022, Arabian Journal of ChemistryCitation Excerpt :The left ventricular papillary muscles were exposed and isolated to be placed in a physiological salt solution in an organ bath as described by Yarmohammadi et al. (Yarmohmmadi, Rahimi et al. 2017, Sheibani, Nezamoleslami et al. 2020). The cold oxygenated physiological salt solution (PSS) was aerated with O2 (95%) and CO2 (5%) and includes the followings in mmol/l: NaCl, 112; KCl, 5; CaCl2, 1.8; MgCl2, 1; NaH2PO4, 0.5; KH2PO4, 0.5; NaHCO3, 25; glucose, 10; and EDTA, 0.004 (pH = 7.4) (Ma, Miyamoto et al. 1996). To obtain the maximum contractile force, the papillary muscles were connected to an isometric force transducer vertically under a resting tension of 500 mg.
Cirrhotic cardiomyopathy
2022, Cardio-Hepatology: Connections Between Hepatic and Cardiovascular DiseaseMechanistic insights into the pathophysiology of cirrhotic cardiomyopathy
2022, Analytical BiochemistryAssociation between cardiac dysfunction, arrhythmias and chronic liver diseases: A narrative review
2020, Trends in Anaesthesia and Critical CareCitation Excerpt :They also modify membrane fluidity and generate reactive oxygen species [77]. In a study, Ma et al. found that factors that play a vital role in the pathogenesis of CCM are the contractile element of heart which is impaired in cirrhosis, along with, altered β-AR signaling function and guanine nucleotide-binding protein expression [78]. In an experiment conducted on mice, Desai et al. showed that 3, 5-diethoxycarbonyl-1, 4-dihydroxychollidine supplemented feeding-induced biliary fibrosis leads to multiple functional, electrophysiological, metabolic, and hypertrophic adaptations in the mouse heart recapping some of the characteristics of human CCM [79].
Cardiopulmonary Complications of Cirrhosis
2017, Zakim and Boyer's Hepatology: A Textbook of Liver Disease