JAPANESE CIRCULATION JOURNAL
Online ISSN : 1347-4839
Print ISSN : 0047-1828
ISSN-L : 0047-1828
Case Reports
Microvascular Ischemia in Patients With Myotonic Dystrophy
Hideki ItohMasami ShimizuYuki HoritaHidekazu InoTomio TaguchiKouji KajinamiKunimasa YagiDaisuke ChujoHiroshi Mabuchi
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JOURNAL FREE ACCESS

2000 Volume 64 Issue 9 Pages 720-722

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Abstract

Two women with myotonic dystrophy underwent dipyridamole thallium-201 (201Tl) myocardial perfusion imaging, after which one patient developed flat T waves in lead I and aVL, and inverted T waves in leads V2-6. The other patient developed a nonspecific intraventricular block that progressed to complete left bundle branch block and was associated with chest discomfort. Reversible scintigraphic defects were observed in both women. Although there was evidence that suggested myocardial ischemia on the ECG changes and 201Tl scintigraphic findings, coronary angiography demonstrated no significant stenoses in either patient. These findings suggest that microvascular dysfunction may lead to myocardial ischemia and conduction disturbances in patients with myotonic dystrophy.

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© 2000 THE JAPANESE CIRCULATION SOCIETY
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