Comparison between strategies using creatine kinase-MB(mass), myoglobin, and troponin T in the early detection or exclusion of acute myocardial infarction in patients with chest pain and a nondiagnostic electrocardiogram

T Jernberg; B Lindahl; S James; G Ronquist; L Wallentin

doi:10.1016/s0002-9149(00)01245-5

Comparison between strategies using creatine kinase-MB(mass), myoglobin, and troponin T in the early detection or exclusion of acute myocardial infarction in patients with chest pain and a nondiagnostic electrocardiogram

Am J Cardiol. 2000 Dec 15;86(12):1367-71, A5. doi: 10.1016/s0002-9149(00)01245-5.

Authors

T Jernberg¹, B Lindahl, S James, G Ronquist, L Wallentin

Affiliation

¹ Department of Cardiology, Cardiothroacic Center, University Hospital, Uppsala, Sweden. tomas.jernberg@medsci.uu.se

PMID: 11113415
DOI: 10.1016/s0002-9149(00)01245-5

Abstract

Different strategies using creatine kinase-MB(mass), myoglobin, and troponin T were compared in 738 patients admitted because of chest pain and an electrocardiogram not diagnostic of acute myocardial infarction. We conclude that a combination of creatine kinase-MB and troponin T during the first 6 hours enables early detection or exclusion of acute myocardial infarction in this population.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Angina Pectoris / blood
Angina Pectoris / diagnosis*
Angina, Unstable / blood
Angina, Unstable / diagnosis
Area Under Curve
Creatine Kinase / blood*
Creatine Kinase, MB Form
Diagnosis, Differential
Electrocardiography*
Female
Humans
Isoenzymes / blood*
Male
Myocardial Infarction / blood
Myocardial Infarction / diagnosis*
Myoglobin / blood*
Predictive Value of Tests
Prognosis
ROC Curve
Sensitivity and Specificity
Time Factors
Troponin T / blood*

Substances

Isoenzymes
Myoglobin
Troponin T
Creatine Kinase
Creatine Kinase, MB Form