Previous studies have documented the safety of magnetic resonance imaging (MRI) of stents in vitro, when placed in animals in vivo, and in patients after elective stent placement. The safety of imaging patients' with stents early after myocardial infarction (MI) has not been examined. We studied 13 patients in an MRI study of myocardial viability on day 3 +/- 1 after stent placement for acute MI. No patient had any clinical events in the early post-MI period, and only 1 of 13 patients demonstrated in-stent restenosis with a mean follow-up of 7 +/- 2 months. For comparison, a group of 17 patients studied concurrently at Allegheny General Hospital as part of the Stent PAMI study, without undergoing MRI, suffered two early deaths and three episodes of in-stent restenosis within 6 months. Based on a review of the literature and this preliminary study, recent stent placement for acute MI should not be considered a contraindication to MRI.