Abstract
In order to evaluate the effect of marine n-3 polyunsaturated fatty acids (n-3 PUFA) on systolic left ventricular function, we investigated the effect of daily supplementation with 5.2 g n-3 PUFA for 12 weeks in 55 patients with a recent myocardial infarction in a double blind placebo-controlled design. Left ventricular function was assessed by transthoracal echo-cardiography and plasma concentration of proANP and N-terminal proANP. No effect of n-3 PUFA could be demonstrated on these indices of left ventricular function.
Publication types
-
Clinical Trial
-
Comparative Study
-
Randomized Controlled Trial
MeSH terms
-
Aged
-
Dietary Supplements*
-
Double-Blind Method
-
Drug Administration Schedule
-
Echocardiography
-
Fatty Acids, Omega-3 / therapeutic use*
-
Female
-
Follow-Up Studies
-
Humans
-
Male
-
Middle Aged
-
Myocardial Infarction / complications
-
Myocardial Infarction / diagnosis
-
Myocardial Infarction / drug therapy*
-
Probability
-
Reference Values
-
Statistics, Nonparametric
-
Treatment Outcome
-
Ventricular Dysfunction, Left / diagnosis*
-
Ventricular Dysfunction, Left / drug therapy*
-
Ventricular Dysfunction, Left / etiology