Multivessel off-pump revascularization in octogenarians: early and midterm outcomes

Ann Thorac Surg. 2003 Jul;76(1):12-7; discussion 17. doi: 10.1016/s0003-4975(03)00014-6.

Abstract

Background: Octogenarians are increasingly being referred for coronary artery revascularization. However, the prevalence of comorbid events and the propensity for neurologic dysfunction place octogenarians at higher risk for cardiopulmonary bypass-induced morbidity and mortality. Therefore, octogenarian patients represent a particularly attractive target for application of off-pump coronary artery bypass grafting.

Methods: From January 1999 to August 2001, 113 octogenarians had off-pump coronary artery bypass grafting. Their data were prospectively entered into the cardiac surgery database and analyzed retrospectively. Follow-up information was obtained through telephone survey.

Results: The mean age of the patients was 83 +/- 2.5 years, and the mean number of grafts per patient was 3.3 +/- 1. The most prevalent postoperative complication was atrial fibrillation (43%). Postoperative neurologic complications were seen in 5 patients (4%). There was one postoperative death (30-day mortality rate, 0.9%). The mean follow-up was 13.2 +/- 7 months and was complete for 90% of the patients. At the time of telephone survey, 85 (87%) of 98 patients were free from angina, and 91 (88%) were free from cardiac-related readmission. There were three late deaths. The majority of octogenarians (66%) reported that in retrospect, they would have the operation again.

Conclusions: Off-pump multivessel revascularization in octogenarians is associated with excellent early and intermediate outcomes and provides a satisfactory quality of life.

MeSH terms

  • Age Factors
  • Aged
  • Aged, 80 and over
  • Cohort Studies
  • Coronary Artery Bypass / adverse effects
  • Coronary Artery Bypass / methods*
  • Coronary Artery Bypass / mortality
  • Coronary Disease / pathology*
  • Coronary Disease / surgery*
  • Female
  • Geriatric Assessment
  • Graft Rejection
  • Graft Survival
  • Heart-Lung Machine
  • Hospital Mortality / trends
  • Humans
  • Intraoperative Complications / epidemiology
  • Length of Stay
  • Male
  • Postoperative Complications / diagnosis
  • Postoperative Complications / epidemiology*
  • Prognosis
  • Quality of Life
  • Retrospective Studies
  • Risk Assessment
  • Survival Analysis