Effect of aortic valve replacement on c-reactive protein in nonrheumatic aortic stenosis

Ivor L Gerber; Ralph A H Stewart; Christopher J K Hammett; Malcolm E Legget; Helen Oxenham; Teena M West; John K French; Harvey D White

doi:10.1016/j.amjcard.2003.07.012

Effect of aortic valve replacement on c-reactive protein in nonrheumatic aortic stenosis

Am J Cardiol. 2003 Nov 1;92(9):1129-32. doi: 10.1016/j.amjcard.2003.07.012.

Authors

Ivor L Gerber¹, Ralph A H Stewart, Christopher J K Hammett, Malcolm E Legget, Helen Oxenham, Teena M West, John K French, Harvey D White

Affiliation

¹ Cardiology Department, Green Lane Hospital, Auckland, New Zealand.

PMID: 14583374
DOI: 10.1016/j.amjcard.2003.07.012

Abstract

Plasma levels of C-reactive protein were higher in 20 patients with bicuspid or trileaflet degenerative aortic stenosis than in 31 normal controls and in 19 patients with pure aortic regurgitation. C-reactive protein decreased from before to 6 months after aortic valve replacement for aortic stenosis. These observations suggest that aortic stenosis is an inflammatory disease.

MeSH terms

Adult
Aged
Aortic Valve Insufficiency / blood*
Aortic Valve Insufficiency / diagnosis
Aortic Valve Insufficiency / surgery*
Aortic Valve Stenosis / blood*
Aortic Valve Stenosis / diagnosis
Aortic Valve Stenosis / surgery*
C-Reactive Protein / metabolism*
Female
Heart Valve Prosthesis Implantation*
Humans
Male
Middle Aged
Rheumatic Heart Disease / blood
Rheumatic Heart Disease / diagnosis
Rheumatic Heart Disease / surgery
Severity of Illness Index

Substances

C-Reactive Protein