Catheter-directed contrast-enhanced coronary MR angiography in swine using magnetization-prepared True-FISP

Magn Reson Med. 2003 Dec;50(6):1317-21. doi: 10.1002/mrm.10642.

Abstract

Contrast-enhanced (CE) coronary magnetic resonance angiography (MRA) following intraarterial (IA) injection of contrast agent was compared using two sequences in swine: magnetization-prepared fast imaging with steady-state precession (True-FISP), and magnetization-prepared fast low-angle shot (FLASH). Thick-slice projection images were acquired with submillimeter in-plane spatial resolution (0.9 x 0.8 mm(2)). The magnetization-preparation scheme provided a clear delineation of the major coronary arteries with excellent background suppression. The True-FISP acquisition resulted in an increase in signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) by approximately a factor of 2 over FLASH (P < 0.05). Magnetization-prepared True-FISP is a promising technique for catheter-directed CE thick-slice projection coronary MRA.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Catheterization
  • Contrast Media / administration & dosage*
  • Coronary Angiography
  • Coronary Vessels / anatomy & histology*
  • Gadolinium DTPA* / administration & dosage
  • Injections, Intra-Arterial
  • Magnetic Resonance Angiography* / methods
  • Swine

Substances

  • Contrast Media
  • Gadolinium DTPA