Randomized comparison of rapid ambulation using radial, 4 French femoral access, or femoral access with AngioSeal closure

Catheter Cardiovasc Interv. 2004 Jun;62(2):143-9. doi: 10.1002/ccd.20027.

Abstract

Radial access and closure devices are associated with improved quality of life (QOL) after cardiac catheterization. Whether this is related to the access site or time to ambulation is unknown. Seventy-five patients undergoing cardiac catheterization were randomized to femoral 6 Fr with AngioSeal closure (F+C), femoral 4 Fr without closure, and radial (R) access. All patients were ambulated at 1 hr. QOL was measured utilizing visual analogue scales and Short Form-36 at baseline, 1 day, and 1 week. Time to ambulation and discharge were equivalent, as was postprocedure QOL. However, angiographic quality was lower in the 4 Fr group (P < 0.0001) and catheterization costs were higher in the F+C group (P < 0.0001). Ambulation 1 hr after catheterization can be accomplished utilizing radial, femoral 6 Fr with closure device, or femoral 4 Fr access with equivalent outcomes and QOL. However, this is achieved at a higher cost with a closure device, or lesser angiographic quality with 4 Fr catheters.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Angioplasty, Balloon, Coronary
  • Cardiac Catheterization* / economics
  • Cardiac Catheterization* / instrumentation
  • Coronary Angiography
  • Coronary Disease / diagnostic imaging
  • Coronary Disease / therapy
  • Early Ambulation* / economics
  • Equipment Design / economics
  • Female
  • Femoral Artery / diagnostic imaging
  • Femoral Artery / physiopathology*
  • Femoral Artery / surgery*
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Myocardial Infarction / diagnostic imaging
  • Myocardial Infarction / therapy
  • Peripheral Vascular Diseases / diagnostic imaging
  • Peripheral Vascular Diseases / physiopathology
  • Peripheral Vascular Diseases / surgery
  • Postoperative Complications / diagnostic imaging
  • Postoperative Complications / etiology
  • Quality of Life
  • Radial Artery / diagnostic imaging
  • Radial Artery / physiopathology*
  • Radial Artery / surgery*
  • Sickness Impact Profile
  • Treatment Outcome