Heart block and empirical therapy after transcatheter closure of perimembranous ventricular septal defect

William C L Yip; Frank Zimmerman; Ziyad M Hijazi

doi:10.1002/ccd.20512

Heart block and empirical therapy after transcatheter closure of perimembranous ventricular septal defect

Catheter Cardiovasc Interv. 2005 Nov;66(3):436-41. doi: 10.1002/ccd.20512.

Authors

William C L Yip¹, Frank Zimmerman, Ziyad M Hijazi

Affiliation

¹ Pediatric Cardiology Service, Gleneagles Hospital, Singapore.

PMID: 16216027
DOI: 10.1002/ccd.20512

Abstract

Two patients with perimembranous ventricular septal defects (VSDs) and inlet extension have undergone uncomplicated transcatheter device closure using the Amplatzer membranous VSD device. Both patients developed complete heart block 2-4 days from the closure. Both patients responded well to high-dose intravenous therapy with steroids and high-dose oral anti-inflammatory aspirin. Both patients remain in normal sinus rhythm 8 weeks and 10 months, respectively, from the episode.

Publication types

Case Reports

MeSH terms

Aspirin / therapeutic use*
Cardiac Catheterization / adverse effects*
Cardiac Surgical Procedures / adverse effects*
Cardiac Surgical Procedures / methods
Child, Preschool
Drug Therapy, Combination
Electrocardiography
Female
Glucocorticoids / therapeutic use*
Heart Block / drug therapy
Heart Block / etiology*
Heart Block / physiopathology
Heart Rate / physiology
Heart Septal Defects, Ventricular / surgery*
Humans
Infant
Platelet Aggregation Inhibitors / therapeutic use*

Substances

Glucocorticoids
Platelet Aggregation Inhibitors
Aspirin