Exercise intolerance in adults with congenital heart disease

Konstantinos Dimopoulos; Gerhard-Paul Diller; Massimo F Piepoli; Michael A Gatzoulis

doi:10.1016/j.ccl.2006.08.002

Exercise intolerance in adults with congenital heart disease

Cardiol Clin. 2006 Nov;24(4):641-60, vii. doi: 10.1016/j.ccl.2006.08.002.

Authors

Konstantinos Dimopoulos¹, Gerhard-Paul Diller, Massimo F Piepoli, Michael A Gatzoulis

Affiliation

¹ Adult Congenital Heart Programme, Department of Cardiology, Royal Brompton Hospital, Sydney Street, London, UK. k.dimopoulos@ic.ac.uk

PMID: 17098517
DOI: 10.1016/j.ccl.2006.08.002

Abstract

This article describes the ways to assess exercise capacity in adults with congenital heart disease (ACHD) and the impact of exercise intolerance in the population. It also discusses the likely pathogenesis of exercise intolerance in ACHD, the similarities between ACHD and acquired heart failure, and potential therapeutic options.

MeSH terms

Adult
Baroreflex
Cyanosis / physiopathology
Cytokines / physiology
Exercise Test / methods
Exercise Therapy
Exercise Tolerance / physiology*
Heart Defects, Congenital / complications
Heart Defects, Congenital / physiopathology*
Heart Rate
Humans
Prognosis
Pulmonary Ventilation / physiology

Substances

Cytokines