Treatment of right ventricular dysfunction in pulmonary arterial hypertension: theoretical considerations

Med Hypotheses. 2009 Sep;73(3):448-52. doi: 10.1016/j.mehy.2009.03.029. Epub 2009 May 26.

Abstract

Significant progress has been made in the medical therapy of pulmonary hypertension in recent years, but long term results are still disappointing. We describe the theoretical underpinnings of a surgical procedure which we suggest might prevent or delay the occurrence of right ventricular failure and thereby improve long-term survival in pulmonary arterial hypertension. This is a hypothesis which could be tested in an animal model of this condition.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Humans
  • Hypertension, Pulmonary / complications*
  • Hypertension, Pulmonary / surgery*
  • Models, Cardiovascular*
  • Ventricular Dysfunction, Right / etiology*
  • Ventricular Dysfunction, Right / prevention & control*