Background: The aim of this study was to evaluate if left ventricular (LV) systolic function by tissue Doppler echocardiography at rest and during exercise preoperatively could predict postoperative LV function and thereby be useful in the timing of aortic valve surgery in patients with severe aortic regurgitation.
Methods: In 29 patients (median age, 59 years; interquartile range, 39-64 years), echocardiography, tissue Doppler echocardiography, and radionuclide ventriculography were performed preoperatively and postoperatively at rest and during supine bicycle exercise.
Results: Preoperative ejection fraction (EF) was 62%. Patients formed two groups, with basal LV peak systolic velocity (PSV) 5.9 cm/s preoperatively as the cutoff value between low and high PSV. Preoperatively, patients with low PSV had lower PSV during exercise (P < .005), EF during exercise (P < .05), and atrioventricular plane displacement (AVPD) at rest (P < .005) and during exercise (P < .05) than those with high PSV. Postoperatively, patients with low PSV had smaller AVPD at rest (P < .05), AVPD during exercise (P < .01), and PSV during exercise (P < .01).
Conclusion: In patients with chronic aortic regurgitation with EFs and LV dimensions not fulfilling criteria for surgery according to guidelines, preoperative PSV and AVPD at rest and during exercise detected postoperative LV dysfunction.
Copyright 2010 American Society of Echocardiography. Published by Mosby, Inc. All rights reserved.