Aneurysms of the left sinus of Valsalva are exceptional. They may cause aortic regurgitation and may rupture into an extra or intra-cardiac location. We report an aneurysm of the left Sinus of Valsalva associated with 3 unusual complications: rupture into the left atrium, infected rupture into the left ventricle inducing aortic regurgitation and compression of the left circumflex coronary artery. These caused cardiac failure, coronary insufficiency and paroxysmal ventricular fibrillation. A review of the literature on the LASV has been undertaken.