Aim: The aim of this study was to examine change in sexual activity before and after cardiac diagnosis in men and women by medication class.
Background: Decline in sexual activity after cardiac diagnosis frequently occurs, with adverse effects of medications believed to play a role, although literature by subclass of drugs are conflicting.
Methods: Mixed methods approach was used to evaluate cardiac patients' (N=211) self-reported medications and changes in sexual activity before and after cardiac diagnosis via mailed survey. Chi square, logistic regression, and thematic analysis were used.
Results: First and third generation beta blockers, class 1 calcium channel blockers, vasodilators, diuretics, and loop diuretics adversely affected sexual activity. Significant predictors of change in sexual activity were number of medications, education level, and income; the overall model predicted 25.7% of the variance in sexual activity.
Conclusions: Sexual assessment and discussion of sexual concerns and side effects of medications by nurses are important to support sexual function.
Keywords: Cardiovascular diseases; Drug therapy; Sexual activity; Sexual dysfunction.
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