The use of labetalol in the management of cocaine crisis

Ann Emerg Med. 1988 Mar;17(3):282-3. doi: 10.1016/s0196-0644(88)80124-0.

Abstract

We report a case of successful resuscitation and clinical management in a 31-year-old man who allegedly ingested 20 g of cocaine hydrochloride. The physiologic and pharmacologic mechanisms of cocaine toxicity are reviewed. The use of labetalol in resolving the cardiovascular crisis is specifically detailed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cocaine / poisoning*
  • Hematuria / chemically induced
  • Humans
  • Hypertension / chemically induced
  • Hypertension / drug therapy
  • Labetalol / therapeutic use*
  • Male
  • Resuscitation
  • Tachycardia, Supraventricular / chemically induced
  • Tachycardia, Supraventricular / drug therapy

Substances

  • Cocaine
  • Labetalol