Plasma and skeletal muscle electrolytes in patients on long-term diuretic therapy for arterial hypertension and/or congestive heart failure

T Dyckner; P O Wester

doi:10.1111/j.0954-6820.1987.tb10664.x

Plasma and skeletal muscle electrolytes in patients on long-term diuretic therapy for arterial hypertension and/or congestive heart failure

Acta Med Scand. 1987;222(3):231-6. doi: 10.1111/j.0954-6820.1987.tb10664.x.

Authors

T Dyckner¹, P O Wester

Affiliation

¹ Department of Internal Medicine, University of Umeå, Sweden.

PMID: 3425378
DOI: 10.1111/j.0954-6820.1987.tb10664.x

Abstract

Investigations regarding plasma and skeletal muscle electrolytes were carried out in 537 patients on long-term diuretic treatment (greater than 1 year) for arterial hypertension (n = 240) and/or congestive heart failure (n = 297). In both groups there were significant decreases in both plasma and skeletal muscle K and Mg, while the muscle Na values as well as the total and extracellular water content of skeletal muscle were increased.

MeSH terms

Aged
Benzothiadiazines*
Body Water / metabolism
Diuretics
Electrolytes / metabolism*
Extracellular Space / metabolism
Female
Heart Failure / drug therapy*
Heart Failure / metabolism
Humans
Hypertension / drug therapy*
Hypertension / metabolism
Male
Middle Aged
Muscles / metabolism*
Sodium Chloride Symporter Inhibitors / adverse effects
Sodium Chloride Symporter Inhibitors / therapeutic use*
Time Factors

Substances

Benzothiadiazines
Diuretics
Electrolytes
Sodium Chloride Symporter Inhibitors