Abstract
Myocardial glycogen content was increased from a mean of 25.8 +/- 3.7 to 40.3 +/- 4.2 mumol/gm (p less than 0.0001) by an infusion of glucose, insulin, and potassium before mitral valve replacement. Patients who had received such an infusion and who had a higher myocardial glycogen content had a lower incidence of postoperative hypotension, less serious postoperative arrhythmias, and fewer serious complications after elective mitral valve replacement.
Publication types
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Clinical Trial
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Comparative Study
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Randomized Controlled Trial
MeSH terms
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Adolescent
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Adult
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Aged
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Female
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Glucose / administration & dosage*
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Glycogen / analysis*
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Heart Valve Prosthesis*
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Humans
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Insulin / administration & dosage*
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Male
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Middle Aged
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Mitral Valve / surgery*
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Myocardium / analysis*
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Postoperative Complications / etiology*
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Potassium / administration & dosage*
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Preoperative Care*
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Prospective Studies
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Risk
Substances
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Insulin
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glucose-insulin-potassium cardioplegic solution
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Glycogen
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Glucose
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Potassium