The quality of life of patients with life-threatening arrhythmias

Arch Intern Med. 1995 Oct 23;155(19):2086-91.

Abstract

Background: The treatment of life-threatening arrhythmias with amiodarone or an implantable cardioverter/defibrillator prolongs patient survival but with significant comorbidity. Previous studies have shown diminished health status and increased psychologic distress and inferred a diminished quality of life; however, a multidimensional analysis of quality of life, including patient perception, has not been performed.

Methods: One hundred four consecutive patients were surveyed regarding patient demographics, health status, psychologic distress, and patient-perceived quality of life. The patients were treated with amiodarone (n = 30) with an implantable cardioverter/defibrillator (n = 45) and the remainder were reference patients (n = 29).

Results: This study confirms that patients who survive life-threatening arrhythmias have diminished health status and increased psychologic distress; however, patient-perceived quality of life is preserved. These patients report a better perceived quality of life (as measured by the Quality of Life Index) than the reference group (22.3 +/- 4.0 vs 20.5 +/- 4.4, P < .05) and their scores are similar to those of normal healthy volunteers (mean score, 21.9). The improved quality of life scores were not dependent on treatment modality (22.1 +/- 4.0 vs 22.4 +/- 4.1 for medical vs surgical groups, respectively).

Conclusions: Patient-perceived quality of life is maintained in patients who survive life-threatening arrhythmias despite their diminished health status and increased psychologic distress. Measured quality of life is independent of treatment modality. Thus, caution must be exercised in assuming a diminished quality of life in patients who have survived a life-threatening cardiac event.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Amiodarone / therapeutic use
  • Anti-Arrhythmia Agents / therapeutic use
  • Arrhythmias, Cardiac / psychology*
  • Arrhythmias, Cardiac / therapy
  • Defibrillators, Implantable
  • Electric Countershock / instrumentation
  • Female
  • Humans
  • Male
  • Middle Aged
  • Quality of Life*
  • Stress, Psychological / etiology*
  • Surveys and Questionnaires

Substances

  • Anti-Arrhythmia Agents
  • Amiodarone