Abstract
Nineteen infants < 6 months old who had atrial ectopic tachycardia (AET) were treated with antiarrhythmic drugs. AET was controlled with digoxin in 1 patient, propafenone in 2, digoxin with propafenone in 9, digoxin with amiodarone in 4, and digoxin with propafenone and amiodarone in 2; radiofrequency ablation was performed in 1 drug-resistant case. AET resolved in 14 of 15 infants within 1 year. Drug side effects occurred in 5 patients. We conclude that AET in infants < 6 months old can be successfully treated with antiarrhythmic drugs, and we recommend a three-step approach with digoxin, a class 1C antiarrhythmic drug, and a class 3 drug. Resolution of AET in infants is frequent.
MeSH terms
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Amiodarone / administration & dosage
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Amiodarone / adverse effects
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Amiodarone / therapeutic use
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Anti-Arrhythmia Agents / therapeutic use*
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Catheter Ablation
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Digoxin / administration & dosage
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Digoxin / adverse effects
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Digoxin / therapeutic use
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Drug Combinations
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Drug Resistance
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Echocardiography
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Electrocardiography
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Electrocardiography, Ambulatory
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Female
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Follow-Up Studies
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Humans
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Infant
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Male
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Propafenone / administration & dosage
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Propafenone / adverse effects
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Propafenone / therapeutic use
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Remission Induction
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Tachycardia, Ectopic Atrial / drug therapy*
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Tachycardia, Ectopic Atrial / surgery
Substances
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Anti-Arrhythmia Agents
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Drug Combinations
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Propafenone
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Digoxin
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Amiodarone