Abstract
Gentianella alborosea ("Hercampure") is a Peruvian species used in folk medicine for the treatment of a variety of health disorders. We tested the free radical scavenging (DPPH) and induction of apoptosis on a human uterus tumor cell line (HeLa) by its methanolic extract. The results showed a noticeable radical scavenging activity and a dose-dependent apoptotic effect.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents, Phytogenic / administration & dosage
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Antineoplastic Agents, Phytogenic / pharmacology*
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Antineoplastic Agents, Phytogenic / therapeutic use
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Apoptosis / drug effects
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Biphenyl Compounds
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Dose-Response Relationship, Drug
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Female
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Free Radical Scavengers / administration & dosage
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Free Radical Scavengers / pharmacology*
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Free Radical Scavengers / therapeutic use
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Gentianella*
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HeLa Cells / drug effects
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Humans
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Medicine, Traditional
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Peru
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Phytotherapy*
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Picrates / chemistry
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Plant Extracts / administration & dosage
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Plant Extracts / pharmacology*
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Plant Extracts / therapeutic use
Substances
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Antineoplastic Agents, Phytogenic
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Biphenyl Compounds
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Free Radical Scavengers
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Picrates
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Plant Extracts
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1,1-diphenyl-2-picrylhydrazyl