Angiogenesis and pericytes in the initiation of ectopic calcification
GDM Collett, AE Canfield - Circulation research, 2005 - Am Heart Assoc
Ectopic calcification of blood vessels, heart valves, and skeletal muscle is a major clinical
problem. There is now good evidence that angiogenesis is associated with ectopic …
problem. There is now good evidence that angiogenesis is associated with ectopic …
Vascular pericytes express osteogenic potential in vitro and in vivo
MJ Doherty, BA Ashton, S Walsh… - Journal of Bone and …, 1998 - academic.oup.com
At postconfluence, cultured bovine pericytes isolated from retinal capillaries form three‐
dimensional nodule‐like structures that mineralize. Using a combination of Northern and …
dimensional nodule‐like structures that mineralize. Using a combination of Northern and …
Gene expression during vascular pericyte differentiation
MJ Doherty, AE Canfield - Critical Reviews™ in Eukaryotic …, 1999 - dl.begellhouse.com
Pericytes, an integral part of the microvasculature, are involved in a number of different
processes, including angiogenesis. Many of the early studies on these cells are descriptive …
processes, including angiogenesis. Many of the early studies on these cells are descriptive …
1α,25-Dihydroxyvitamin D3 Inhibits Angiogenesis In Vitro and In Vivo
DJ Mantell, PE Owens, NJ Bundred, EB Mawer… - Circulation …, 2000 - Am Heart Assoc
Modulation of angiogenesis is now a recognized strategy for the prevention and treatment of
pathologies categorized by their reliance on a vascular supply. The purpose of this study …
pathologies categorized by their reliance on a vascular supply. The purpose of this study …
Role of pericytes in vascular calcification: a review
AE Canfield, MJ Doherty, AC Wood, C Farrington… - Zeitschrift für …, 2000 - Springer
Pericytes are defined by their location in vivo; the pericyte partially surrounds the endothelial
cell of the microvessel and shares a common basement membrane with it. As an integral …
cell of the microvessel and shares a common basement membrane with it. As an integral …
Chondrogenic and adipogenic potential of microvascular pericytes
C Farrington-Rock, NJ Crofts, MJ Doherty, BA Ashton… - Circulation, 2004 - Am Heart Assoc
Background—Previous studies have shown that pericytes can differentiate into osteoblasts
and form bone. This study investigated whether pericytes can also differentiate into …
and form bone. This study investigated whether pericytes can also differentiate into …
Calcification is associated with loss of functional calcium-sensing receptor in vascular smooth muscle cells
M Alam, JP Kirton, FL Wilkinson, E Towers… - Cardiovascular …, 2009 - academic.oup.com
Aims Vascular calcification (VC) is highly correlated with increased morbidity and mortality in
advanced chronic kidney disease (CKD) patients. Allosteric modulation of the calcium …
advanced chronic kidney disease (CKD) patients. Allosteric modulation of the calcium …
Pericytes derived from the retinal microvasculature undergo calcification in vitro
AM Schor, TD Allen, AE Canfield… - Journal of cell …, 1990 - journals.biologists.com
Pericytes isolated from the bovine retinal microvasculature retain characteristic features of
their in vivo counterparts, such as the presence of glycogen deposits, long filamentous …
their in vivo counterparts, such as the presence of glycogen deposits, long filamentous …
A novel hyaluronan-based biomaterial (Hyaff-11®) as a scaffold for endothelial cells in tissue engineered vascular grafts
NJ Turner, CM Kielty, MG Walker, AE Canfield - Biomaterials, 2004 - Elsevier
Current prosthetic small diameter vascular grafts show poor long-term patency rates, leading
to the pursuit of a biological alternative. Hyaff-11 is a hyaluronan-based biodegradable …
to the pursuit of a biological alternative. Hyaff-11 is a hyaluronan-based biodegradable …
Wnt/β-catenin signaling stimulates chondrogenic and inhibits adipogenic differentiation of pericytes: potential relevance to vascular disease?
JP Kirton, NJ Crofts, SJ George, K Brennan… - Circulation …, 2007 - Am Heart Assoc
The aberrant differentiation of pericytes along the adipogenic, chondrogenic, and
osteogenic lineages may contribute to the development and progression of several vascular …
osteogenic lineages may contribute to the development and progression of several vascular …