Background Even before the onset of age-related diseases, obesity might be a contributing
factor to the cumulative burden of oxidative stress and chronic inflammation throughout the …

Telomeres are involved in maintaining genomic stability. Previous studies have linked both
telomere length (TL) and telomere‐related genes with cancer. We evaluated associations …

Aims/hypothesis Epidemiological studies have generated conflicting findings on the
relationship between glucose-lowering medication use and cancer risk. Naturally occurring …

Clinical education presents a unique learning experience in contrast to the classroom-based
teaching approach. Clinical education represents a less controlled learning environment …

Background The TGFβ-signaling pathway plays an important role in the pathogenesis of
colorectal cancer (CRC). Loss of function of several genes within this pathway, such as bone …

Background Telomeres cap the ends of chromosomes and help maintain genomic stability
and integrity. Telomere length (TL) has been linked to a number of diseases, including a …

Background Epidemiological and experimental evidence suggests that higher folate intake
is associated with decreased colorectal cancer (CRC) risk; however, the mechanisms …

Selenoproteins are a class of proteins containing a selenocysteine residue, many of which
have been shown to have redox functions, acting as antioxidants to decrease oxidative …

Glucocorticoids regulate hippocampal function in part by modulating gene expression
through the glucocorticoid receptor (GR). GR binding is highly cell type specific, directed to …

Half of miRNAs expressed in colorectal tissue are expressed< 50% of the population. Many
infrequently expressed miRNAs have low levels of expression. We hypothesize that less …