A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human
genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion …

Chronic kidney disease is defined as a reduced glomerular filtration rate, increased urinary
albumin excretion, or both, and is an increasing public health issue. Prevalence is estimated …

Context Although technology-enhanced simulation has widespread appeal, its effectiveness
remains uncertain. A comprehensive synthesis of evidence may inform the use of simulation …

Genetic variants that inactivate protein-coding genes are a powerful source of information
about the phenotypic consequences of gene disruption: genes that are crucial for the …

Anopheles gambiae is the principal vector of malaria, a disease that afflicts more than 500
million people and causes more than 1 million deaths each year. Tenfold shotgun sequence …

For natural language understanding (NLU) technology to be maximally useful, both
practically and as a scientific object of study, it must be general: it must be able to process …

Background We sought to provide a contemporary picture of the presentation, etiology, and
outcome of infective endocarditis (IE) in a large patient cohort from multiple locations …

Reduced fecundity, associated with severe mental disorders, places negative selection
pressure on risk alleles and may explain, in part, why common variants have not been found …

Background The role of endovascular therapy for acute stroke with a large infarction has not
been extensively studied in differing populations. Methods We conducted a multicenter …

Summary Background In May, 2022, several European countries reported autochthonous
cases of monkeypox, which rapidly spread globally. Early reports suggest atypical …