An increased or disturbed activation and aggregation of platelets plays a major role in the
pathophysiology of thrombosis and haemostasis and is related to cardiovascular disease …

There is a large literature on the productivity of universities. Little is known, however, about
how different types of leader affect a university's later performance. To address this, I blend …

Obesity is heritable and predisposes to many diseases. To understand the genetic basis of
obesity better, here we conduct a genome-wide association study and Metabochip meta …

Coronary artery disease (CAD) is the commonest cause of death. Here, we report an
association analysis in 63,746 CAD cases and 130,681 controls identifying 15 loci reaching …

Interest in leadership development in healthcare is substantial. Yet it remains unclear which
interventions are most reliably associated with positive outcomes. We focus on the important …

Background Obesity is a major health problem that is determined by interactions between
lifestyle and environmental and genetic factors. Although associations between several …

Eukaryotic chromosomes end with telomeres, which shorten with cellular ageing. We
investigated whether atherosclerosis is associated with systemic evidence of accelerated …

Objective—Biological age may be distinct from chronological age and contribute to the
pathogenesis of age-related diseases. Mean telomeres lengths provide an assessment of …

The number and volume of cells in the blood affect a wide range of disorders including
cancer and cardiovascular, metabolic, infectious and immune conditions. We consider here …

Platelets are the second most abundant cell type in blood and are essential for maintaining
haemostasis. Their count and volume are tightly controlled within narrow physiological …