[HTML][HTML] Cardiac amyloidosis

A Martinez-Naharro, PN Hawkins, M Fontana - Clinical Medicine, 2018 - ncbi.nlm.nih.gov
Systemic amyloidosis comprises an uncommon group of disorders caused by the
extracellular deposition of misfolded proteins in various organs. Cardiac amyloid deposition …

Diagnostic imaging of cardiac amyloidosis

A Martinez-Naharro, AJ Baksi, PN Hawkins… - Nature Reviews …, 2020 - nature.com
Systemic amyloidosis encompasses a debilitating, under-diagnosed but increasingly
recognized group of disorders characterized by the extracellular deposition of misfolded …

A new staging system for cardiac transthyretin amyloidosis

JD Gillmore, T Damy, M Fontana… - European heart …, 2018 - academic.oup.com
Aims Cardiac transthyretin (ATTR) amyloidosis is an increasingly recognized, progressive,
and fatal cardiomyopathy, the natural history of which remains unclear. We sought to …

Magnetic resonance in transthyretin cardiac amyloidosis

A Martinez-Naharro, TA Treibel, A Abdel-Gadir… - Journal of the American …, 2017 - jacc.org
Background: Cardiac transthyretin amyloidosis (ATTR) is an increasingly recognized cause
of heart failure. Cardiac magnetic resonance (CMR), with late gadolinium enhancement …

Natural history, quality of life, and outcome in cardiac transthyretin amyloidosis

T Lane, M Fontana, A Martinez-Naharro, CC Quarta… - Circulation, 2019 - Am Heart Assoc
Background: Transthyretin amyloidosis cardiomyopathy (ATTR-CM) is an increasingly
recognized cause of heart failure in older individuals. We sought to characterize the natural …

Abnormal lung function in adults with congenital heart disease: prevalence, relation to cardiac anatomy, and association with survival

R Alonso-Gonzalez, F Borgia, GP Diller, R Inuzuka… - Circulation, 2013 - Am Heart Assoc
Background—Restrictive lung defects are associated with higher mortality in patients with
acquired chronic heart failure. We investigated the prevalence of abnormal lung function, its …

Native T1 and extracellular volume in transthyretin amyloidosis

A Martinez-Naharro, T Kotecha, K Norrington… - JACC: Cardiovascular …, 2019 - jacc.org
Objectives: This study evaluated the prognostic potential of native myocardial T1 in cardiac
transthyretin amyloidosis (ATTR) and compared native T1 with extracellular volume (ECV) in …

Myocardial edema and prognosis in amyloidosis

T Kotecha, A Martinez-Naharro, TA Treibel… - Journal of the American …, 2018 - jacc.org
Background: Prognosis in light-chain (AL) and transthyretin (ATTR) amyloidosis is
influenced by cardiac involvement. ATTR amyloidosis has better prognosis than AL …

Reduction in CMR derived extracellular volume with patisiran indicates cardiac amyloid regression

M Fontana, A Martinez-Naharro, L Chacko… - Cardiovascular …, 2021 - jacc.org
Objectives The purpose of this study was to determine the effect of patisiran on the cardiac
amyloid load as measured by cardiac magnetic resonance and extracellular volume (ECV) …

Antibody-associated reversal of ATTR amyloidosis–related cardiomyopathy

M Fontana, J Gilbertson, G Verona… - … England Journal of …, 2023 - Mass Medical Soc
Antibody-Associated Reversal of ATTR Amyloidosis–Related Cardiomyopathy Page 1 The new
england journal of medicine n engl j med 388;23 nejm.org June 8, 2023 Correspondence …