Aims Although the mechanism is unclear, exposure to traffic-derived air pollution is a trigger
for acute myocardial infarction (MI). The aim of this study is to investigate the effect of diesel …

Aim Exposure to road traffic and air pollution may be a trigger of acute myocardial infarction,
but the individual pollutants responsible for this effect have not been established. We assess …

Background—In controlled human exposure studies, diesel engine exhaust inhalation
impairs vascular function and enhances thrombus formation. The aim of the present study …

Introduction Exposure to air pollution is associated with increased cardiovascular morbidity,
although the underlying mechanisms are unclear. Vascular dysfunction reduces arterial …

Background Traffic emissions including diesel engine exhaust are associated with
increased respiratory and cardiovascular morbidity and mortality. Controlled human …

Immediate assessment of coronary microcirculation during treatment of ST elevation
myocardial infarction (STEMI) may facilitate patient stratification for targeted treatment …

Objective The inflammatory cytokine, tumour necrosis factor α (TNF-α), exerts deleterious
cardiovascular effects. We wished to determine the effects of TNF-α antagonism on …

To investigate the diagnostic accuracy of (1) hyperaemic angiography-derived index of
microcirculatory resistance (IMRangio) in defining coronary microvascular dysfunction …

Background: Rates of myocardial infarction in firefighters are increased during fire
suppression duties, and are likely to reflect a combination of factors including extreme …

Objectives: This study aimed to compare the value of the index of microcirculatory resistance
(IMR) and microvascular obstruction (MVO) measured by cardiac magnetic resonance …