User profiles for "author:Andrew Wragg"
Andrew WraggBarts Heart Centre Verified email at bartshealth.nhs.uk Cited by 10623 |
p53 regulates mitochondrial respiration
S Matoba, JG Kang, WD Patino, A Wragg, M Boehm… - Science, 2006 - science.org
The energy that sustains cancer cells is derived preferentially from glycolysis. This metabolic
change, the Warburg effect, was one of the first alterations in cancer cells recognized as …
change, the Warburg effect, was one of the first alterations in cancer cells recognized as …
A rapid protocol for the prevention of contrast-induced renal dysfunction: the RAPPID study
CSR Baker, A Wragg, S Kumar, R De Palma… - Journal of the American …, 2003 - jacc.org
Objectives: This study was designed to test a rapid protocol of intravenous acetylcysteine for
prevention of radiocontrast-induced nephropathy (RCIN). Background: Oral acetylcysteine …
prevention of radiocontrast-induced nephropathy (RCIN). Background: Oral acetylcysteine …
TGF-β signaling mediates endothelial-to-mesenchymal transition (EndMT) during vein graft remodeling
BC Cooley, J Nevado, J Mellad, D Yang… - Science translational …, 2014 - science.org
Veins grafted into an arterial environment undergo a complex vascular remodeling process.
Pathologic vascular remodeling often results in stenosed or occluded conduit grafts …
Pathologic vascular remodeling often results in stenosed or occluded conduit grafts …
Implementing workplace‐based assessment across the medical specialties in the United Kingdom
JR Wilkinson, JGM Crossley, A Wragg, P Mills… - Medical …, 2008 - Wiley Online Library
Objectives To evaluate the reliability and feasibility of assessing the performance of medical
specialist registrars (SpRs) using three methods: the mini‐clinical evaluation exercise (mini …
specialist registrars (SpRs) using three methods: the mini‐clinical evaluation exercise (mini …
Successful recanalization of chronic total occlusions is associated with improved long-term survival
Objectives: This study investigated the impact of procedural success on mortality following
chronic total occlusion (CTO) percutaneous coronary intervention (PCI) in a large cohort of …
chronic total occlusion (CTO) percutaneous coronary intervention (PCI) in a large cohort of …
Learning systems: managing uncertainty in the new normal of Covid-19
R Bohmer, J Shand, D Allwood, A Wragg… - … Innovations in Care …, 2020 - catalyst.nejm.org
The novel coronavirus has presented considerable challenges to clinicians. In London,
leaders employed a “learning system” model to quickly create and refine a care delivery …
leaders employed a “learning system” model to quickly create and refine a care delivery …
[HTML][HTML] A prospective international multicentre cohort study of intraoperative heart rate and systolic blood pressure and myocardial injury after noncardiac surgery …
TEF Abbott, RM Pearse, RA Archbold… - Anesthesia & …, 2018 - journals.lww.com
BACKGROUND: The association between intraoperative cardiovascular changes and
perioperative myocardial injury has chiefly focused on hypotension during noncardiac …
perioperative myocardial injury has chiefly focused on hypotension during noncardiac …
Acute myocarditis presenting as acute coronary syndrome: role of early cardiac magnetic resonance in its diagnosis
PA Monney, N Sekhri, T Burchell, C Knight, C Davies… - Heart, 2011 - heart.bmj.com
Background In patients presenting with acute cardiac symptoms, abnormal ECG and raised
troponin, myocarditis may be suspected after normal angiography. Aims To analyse cardiac …
troponin, myocarditis may be suspected after normal angiography. Aims To analyse cardiac …
Integrating CT myocardial perfusion and CT-FFR in the work-up of coronary artery disease
A Coenen, A Rossi, MM Lubbers, A Kurata… - JACC: Cardiovascular …, 2017 - jacc.org
Objectives: The aim of this study was to investigate the individual and combined accuracy of
dynamic computed tomography (CT) myocardial perfusion imaging (MPI) and computed …
dynamic computed tomography (CT) myocardial perfusion imaging (MPI) and computed …
Diagnostic performance of hyperaemic myocardial blood flow index obtained by dynamic computed tomography: does it predict functionally significant coronary …
A Rossi, A Dharampal, A Wragg… - European Heart …, 2014 - academic.oup.com
Aims The severity of coronary artery narrowing is a poor predictor of functional significance,
in particular in intermediate coronary lesions (30–70% diameter narrowing). The aim of this …
in particular in intermediate coronary lesions (30–70% diameter narrowing). The aim of this …