Patients with microvascular angina (MVA) often have persistence of symptoms despite full
classical anti-ischemic therapy. In this study, we assessed the effect of ivabradine and …

A large number of studies has demonstrated that abnormalities of coronary microcirculation
may be responsible for both acute and chronic cardiac ischemic syndromes. In clinical …

Background—Cellular studies showed that histone methyltransferase Set7 mediates high
glucose–induced inflammation via epigenetic regulation of the transcription factor NF-kB …

Endothelial dysfunction is an early abnormality in the process of atherosclerosis and
cardiovascular disease and has been associated with worse clinical outcome. Cardiac …

A MVA could be secondary to functional/structural dysfunction of the coronary
microcirculation occurring in the settings of specific cardiac diseases (eg cardiomyopathy) …

Purpose To assess the effects of short-acting nitrates on exercise stress test (EST) results
and the relation between EST results and coronary blood flow (CBF) response to nitrates in …

Aim Diabetes is a major driver of cardiovascular disease, but the underlying mechanisms
remain elusive. Prolyl-isomerase Pin1 recognizes specific peptide bonds and modulates …

Background Between 10 and 15% of patients admitted for non-ST-segment elevation acute
coronary syndrome (NSTE-ACS) show no obstructive coronary artery disease (NO-CAD) at …

Objectives: The aim of our study was to assess the prognostic value of heart rate variability
(HRV) in ST-segment elevation acute myocardial infarction (STEMI) patients treated by …

Background Smoking induces an impairment of endothelium-dependent vasodilatation. In
this study we assessed whether smoking also causes an impairment of endothelium …